Therapeutic apheresis for neuromyelitis optica and neuromyelitis optica spectrum disorders
نویسندگان
چکیده
منابع مشابه
Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate
BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...
متن کاملNeuromyelitis Optica Spectrum Disorders: Diagnosis and Treatment
The last decade has witnessed rapid developments in the clinical understanding and scienti fi c foundati on of neuromyeliti s opti ca (NMO). The landmark events were the late 19th century report by Devic and Gault describing the associati on of severe acute transverse myeliti s and opti c neuriti s and the late 20th century discovery that the syndrome was associated with a specifi c autoanti bo...
متن کاملThe spectrum of neuromyelitis optica.
Neuromyelitis optica (also known as Devic's disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord. Neuromyelitis optica has a worldwide distribution, poor prognosis, and has long been thought of as a variant of multiple sclerosis; however, clinical, laboratory, immunological, and pathological characteri...
متن کاملNeuromyelitis Optica
An 11-year-old girl developed sudden visual loss in her left eye, preceding subacute myelitis by 9 months. Multifocal lesions in the central nervous system were demonstrated by magnetic resonance imaging. Although unilateral blindness is unusual, the clinical findings predominantly involving the optic nerve and spinal cord were consistent with the diagnosis of neuromyelitis optica (NMO). This c...
متن کاملScreening for onconeural antibodies in neuromyelitis optica spectrum disorders
BACKGROUND Some so-called "non-classical" paraneoplastic neurological syndromes (PNS), namely optic neuritis and myelitis, clinically overlap with neuromyelitis optica spectrum disorders (NMOSD), and conversely, in cancer-associated NMOSD, a paraneoplastic etiology has been suggested in rare cases. Therefore, we retrospectively investigated the prevalence of onconeural antibodies, which are hig...
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ژورنال
عنوان ژورنال: Nihon Toseki Igakkai Zasshi
سال: 2012
ISSN: 1340-3451,1883-082X
DOI: 10.4009/jsdt.45.413